Most people just get in line and roll up their sleeves; no questions asked. At the very least, they should read the package insert for the H1N1 vaccine. Actually, it should be a requirement that it be read and explained to them by a doctor or whomever administers the injection. This amounts to a free phase 4 trial for the drug companies. Normally, they would have to give informed consent, pay the victim, and be liable for damages for adverse outcomes. With this travesty, they have pushed through laws that indemnify them from any law suits. If you get Guillain-Barre or some other permanent neuropathy, tough cookies.

We will see worse outcomes than in 1976 from this round of vaccines, I predict. A major reason being that many in the population targeted for the vaccine will already be on immuno-suppressing monoclonal antibody drugs (MAB's). This is a relatively new class of drug that is used for several auto-immune diseases such as rheumatoid arthritis and multiple sclerosis. These drugs selectively blunt the immune system response that is responsible for the inflammation which causes the symptoms in auto-immune disease. These drugs will block specific cytokines such as tumor necrosis factor, disabling their participation in the inflammation process.

The problem is that this leaves the person more vulnerable to overgrowth of resident viruses. One example is the virus that causes progressive multifocal leukoencephalopathy (PML). This is a disease that progressively turns your brain into oatmeal. Its caused by a virus (the JC virus) that normally resides in the brain of most people without causing problems. We see the viral infection become clinical in patients with AIDS, patients undergoing chemotherapy, patients on immono-suppressive drugs after an organ transplant, or patients who are otherwise immuno-compromised. When a person takes a MAB, this immuno-suppression also allows the virus to overgrow. There is no treatment and the disease is fatal in a matter of months. The increased incidence of this disease will not be seen until months after the vaccine has been given. Even then, only the most astute epidemiologist would link the disease to the H1N1 vaccine. 

This will be the case with many viruses that already reside in people, and there are many: cytomegalo virus, Epstein Barr virus, the varicella virus that causes shingles, several types of herpes viruses, papilloma viruses etc. Many of these are associated with increased cancer risk. These are, of course, a concern additional to the problems we face with fungal overgrowth which is a potent immuno-suppressant. Just being hypothyroid can be the first domino to immune compromise as this is associated with fungal overgrowth. Pregnant women are more at risk for hypothyroidism due to the large amounts of estrogen produced during pregnancy. Pregnant women are a target population for the H1N1 vaccine. I have never wanted to be this wrong, but I sure as heck hope that I am completely off base on this one. Otherwise, we are going to witness some catastrophe over the next 6 months. 

THIS link is the package insert for the H1N1 vaccine. Jaw dropping! Read this before you take or administer the H1N1. I recommend you who are pharmacists not even offer it. Previously, I had recommended that health care professionals who were mandated to take it to go ahead and take it. I'm reversing my position after reading this. If you do take it, be sure you have good disability insurance and this is not hyperbole. I would not take this injection if my job depended on it. Some highlights:

- 4-9 year olds have to get 2 injections. Read through the side effects and think about putting a kid through that twice.

- Guillain-Barre is listed as a possible side effect. This is the paralyzing, potentially fatal nerve disease seen with the last swine flu vaccine in 1976. Nerve damage can be permanent.

- The people who need to be protected most, those with compromised immunity, are not likely to benefit from the vaccine.

- In section 6.2, they state that results from a trial with one vaccine can't be used to judge the safety of a similar but different vaccine. Yet, they proceed to do just that by giving results of their Fluvirin vaccine and imply that this is what to expect with the H1N1 vaccine, which has not been tested past initial trials in healthy adults. This wouldn't be allowed in high school science.

- Said Fluvirin vaccine is virtually untested in minorities.

The predominant systemic symptom is neurological. This really points to the MF59 squalene adjuvant precipitating an autoimmune response to native squalene in nerve tissue. You'll note that you are prohibited from giving a gluteal injection, ostensibly to avoid hitting the sciatic nerve. I taught my administrative assistant's husband to safely give a gluteal injection. That should not be a worry for a medical professional unless there is some inherent risk of exposing nerve tissue to this vaccine.

These are neurological symptoms listed for the Fluvirin (seasonal flu vacine). Again, the phase 3 studies have not even been done on the H1N1 vaccine. Nervous system disorders: Headache, dizziness, neuralgia, paraesthesia, confusion, febrile convulsions, Guillain-Barré Syndrome, myelitis (including encephalomyelitis and transverse myelitis), neuropathy (including neuritis), paralysis (including Bell’s Palsy).

Section 7.1 is quite disturbing: 

"Concomitant Administration with Other Vaccines - There are no data to assess the concomitant administration of Influenza A (H1N1) 2009 Monovalent Vaccine with other vaccines. If Influenza A (H1N1) 2009 Monovalent Vaccine is to be given at the same time as another injectable vaccine(s), the vaccines should always be administered at different injection sites."

Let me get this straight - you have no idea what is going to happen when the H1N1 vaccine is given along with the seasonal flu vaccine, and both will be given to immunocompromised children, adults and pregnant women? More good news: It is also not known whether Influenza A (H1N1) 2009 Monovalent Vaccine or FLUVIRIN can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. And, safety and effectiveness in pediatric subjects below the age of 4 years have not been established. Mercury found in fish is deadly and pregnant mothers are warned to avoid fish. Apparently mercury loses its toxicity potential when given with vaccines: The 5-mL multidose vial formulation contains thimerosal, a mercury derivative, added as a preservative. Each 0.5-mL dose from the multidose vial contains 25 mcg mercury.

Now, if you read this part and still administer or take the H1N1 or even the seasonal flu vaccine, you need to re-examine your motives. 

"12.1 Mechanism of Action - Influenza illness and its complications follow infection with influenza viruses. Global surveillance of influenza identifies yearly antigenic variants. For example, since 1977, antigenic variants of influenza A (H1N1 and H3N2) viruses and influenza B viruses have been in global circulation. Specific levels of hemagglutination inhibition (HI) antibody titers post-vaccination with inactivated influenza virus vaccine have not been correlated with protection from influenza illness. In some human studies, antibody titer of ≥1:40 have been associated with protection from influenza illness in up to 50% of subjects [see REFERENCES (15.2, 15.3)].

Antibody against one influenza virus type or subtype confers limited or no protection against another. Furthermore, antibody to one antigenic variant of influenza virus might not protect against a new antigenic variant of the same type or subtype."